Article Correctness Is Author's Responsibility: New Insights on ALS May Point To a Potentially Promising Treatment Strategy

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This shows a brainPost-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell's mitochondria to fragment and increase oxidative stress. Reducing tau reversed the effect, decreasing oxidative stress and mitochondrial fragmentation.